All rights reserved. "The Delta variant poses a serious risk to people who are not fully vaccinated, as . 11 0 obj endobj You can get antigen test results in about 15 minutes, but they tend to be less accurate. %PDF-1.6 % Emerg Infect Dis 2020;26:126673. For those who were asymptomatic at the time of testing, sensitivity was higher when an epidemiological exposure to SARS-CoV-2 was suspected (64.3%, 95% CI 54.6% to 73.0%; 16 evaluations; 7677 samples, 703 cases) compared to where COVID-19 testing was reported to be widely available to anyone on presentation for testing (49.6%, 95% CI 42.1% to 57.1%; 26 evaluations; 31,904 samples, 1758 cases). The goal of testing is to identify people who have an infection with SARS-CoV-2 so they can prevent spreading it to others. The links below include lot numbers and expiration dates for the 15 brands of at-home COVID-19 tests that have had their shelf lives extended by the FDA. US CDC real-time reverse transcription PCR panel for detection of severe acute respiratory syndrome coronavirus 2. Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection. %%EOF This investigation evaluated performance of the Sofia SARS Antigen Fluorescent Immunoassay (FIA) (Quidel Corporation) compared with real-time reverse transcriptionpolymerase chain reaction (RT-PCR) for SARS-CoV-2 detection among asymptomatic and symptomatic persons at two universities in Wisconsin. For the flu, these antigen tests are easy to administer, decently accurate and give . GXZ&Y0``du2RnIKBU|9~8`%#B MxwlC['m#V+GoAl 1O'ehD/j@rf_%SB9- sGja@ Itt aF RLA, @wS&n pY)MJU0v2?p|sXAB Your Expired COVID Test Kits Might Still Be Good. Here's How to Find 107 0 obj The findings in this report are subject to at least four limitations. Beijing Jinwofu Bioengineering Technology Co.,Ltd. Ian W. Pray, PhD1,2,3,*; Laura Ford, PhD1,2,*; Devlin Cole, MD3,4; Christine Lee, PhD1,5; John Paul Bigouette, PhD1,2; Glen R. Abedi, MPH1; Dena Bushman, MSN, MPH1,2; Miranda J. Delahoy, PhD1,2; Dustin Currie, PhD1,2; Blake Cherney, MS1; Marie Kirby, PhD1; Geroncio Fajardo, MD1; Motria Caudill, PhD1,6; Kimberly Langolf, MS7; Juliana Kahrs, MS7; Patrick Kelly, MD4,8; Collin Pitts, MD4,8; Ailam Lim, PhD9; Nicole Aulik, PhD9; Azaibi Tamin, PhD1; Jennifer L. Harcourt, PhD1; Krista Queen, PhD1; Jing Zhang, PhD1; Brett Whitaker, PhD1; Hannah Browne1; Magdalena Medrzycki, PhD1; Patricia Shewmaker, PhD1; Jennifer Folster, PhD1; Bettina Bankamp, PhD1; Michael D. Bowen, PhD1; Natalie J. Thornburg, PhD1; Kimberly Goffard, MBA10; Brandi Limbago, PhD1; Allen Bateman, PhD7,11; Jacqueline E. Tate, PhD1; Douglas Gieryn10; Hannah L. Kirking, MD1; Ryan Westergaard, MD, PhD3,4; Marie Killerby, VetMB1; CDC COVID-19 Surge Laboratory Group (View author affiliations). Get the facts about the 2019 coronavirus (and COVID-19). Australians are being urged to register their positive rapid antigen tests with authorities. Laboratories can reduce backlogs to some extent by adding more equipment and technicians, or by automating procedures. List of approved COVID-19 Antigen Kits [Updated date: 2078-11-02 / 2022 If the test is positive, the color of the fluid in the tube changes yellow. Rapid tests are important since they provide reliable and quick results. Further research is needed to evaluate the effectiveness of screening programmes at reducing transmission of infection, whether mass screening or targeted approaches including schools, healthcare setting and traveller screening. In people with confirmed COVID-19, antigen tests correctly identified COVID-19 infection in an average of 73% of people with symptoms, compared to 55% of people without symptoms. But Bobby Brooke Herrera, PhD, co-founder and CEO of biotech company e25 Bio, told The Atlantic that because the FDA compares newly made coronavirus tests to the PCR test, companies developing tests are focused on accuracy at the cost of speed and convenience. During the defense's cross-examination of E. Jean Carroll, Trump's attorney asked the writer why she "did not scream" when she was "supposedly raped.". ,*, %PDF-1.7 % We tabulated results by test manufacturer and compliance with manufacturer instructions for use and according to symptom status. The N-protein of the SARS-CoV-2 virus reacts with the coating of the test line and leads to a color change, i.e. COVID-19 diagnostic testing - Mayo Clinic Weekly / January 1, 2021 / 69(5152);16421647. Based on our review, your Antibodies Test Kit for Covid19 is intended for use in the mitigation, prevention, treatment, diagnosis, or cure of COVID-19 1 in people, and thus, it is a device under . In this instance, a series of consecutive positive results in asymptomatic persons was noted, and investigators offered repeat antigen testing to the affected participants. By choosing the country the online store will show products eligible for shipping to that country. Symptom list was based on the interim position statement for COVID-19 case definitions from the Council of State and Territorial Epidemiologists, updated August 7, 2020. The median interval from symptom onset to specimen collection was 3 days (interquartile range=16 days; 7.5% missing). All data and statistics are based on publicly available data at the time of publication. Beijing Lepu Medical Technology Co., Ltd. 26. Covid-19 Antigen Rapid Tests - BPS Health What are the limitations of the evidence? Chan School of Public Health in Boston, argues that the United States should be testing nearly everyone in the country almost every day which means running tens of millions of tests a day. COVID-19 Antigen Test Market Demand by 2031 - MarketWatch This test is approved by the Food and Drug Administration (FDA) and is currently one of the more affordable options for at-home testing. endorsement of these organizations or their programs by CDC or the U.S. Two people independently carried out quality assessment (using the QUADAS-2 tool) and extracted study results. Taking your first rapid antigen test? 7 tips for an accurate result endobj No test met this standard when evaluated in people without symptoms. Although antigen tests are faster and the number of tests being run can be easily scaled up, they have a high false-negative rate with as many as half of negative results inaccurate. This corona self-test can be used at home, work, or anywhere where a rapid result is needed. PDF Coronavirus 2019-nCoV Test Gold) Data - KL global medical Severe acute respiratory syndrome coronavirus 2 from patient with coronavirus disease, United States. What are the implications for public health practice? Hotgen COVID-19 Self-test: Test Yourself at Home! - Bioactiva Diagnostica Results are available in 10 minutes, and the On Go test can be found on Amazon for $24.99. These tests identify proteins on the virus in samples taken from the nose or throat. Sensitivity95.37% 99.13% Accuracy: 97.31%. We included evaluations of single applications of a test (one test result reported per person) and evaluations of serial testing (repeated antigen testing over time). 11 Best At-Home COVID-19 Coronavirus Tests 2021 - The Strategist Atlanta, GA: US Department of Health and Human Services, CDC; 2020. Despite reduced sensitivity compared with real-time RT-PCR, the use of antigen tests for serial testing in these settings, particularly when RT-PCR tests are not available or have a prolonged turnaround time, might still allow rapid identification of infectious persons and control of outbreaks (1). On Go At-Home COVID-19 Rapid Antigen Self-Test. Of these, 5 people (11%) would not have COVID-19 (false positive result). https://www.cdc.gov/coronavirus/2019-ncov/if-you-are-sick/steps-when-sick.html. Rapid antigen tests are most accurate when they are used in people who have signs or symptoms of COVID-19, especially during the first week of illness. Antigen tests have received Food and Drug Administration (FDA) Emergency Use Authorization (EUA) for use in asymptomatic and symptomatic persons within the first 512 days after symptom onset (2). Ever in close contact was defined as within 6 feet for 15 minutes of a person with a diagnosis of COVID-19. Art. The test can also be especially beneficial for businesses that are operating during the pandemic, such as medical clinics, retirement homes, therapists, hotels, schools, universities, etc. JAMA 2020;324:17278. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. Gniazdowski V, Morris CP, Wohl S, et al. MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. Performance of an Antigen-Based Test for - CDC Coronavirus disease 2019 (COVID-19): interim guidance for antigen testing for SARS-CoV-2. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. endobj Ninety-five percent confidence intervals (CIs) were calculated using the exact binomial method; t-tests were used for Ct value comparisons; p-values <0.05 were considered statistically significant. The at-home antigen test: What do experts think, and how do you use The test was compared against RT-PCR results in 223 patients and was found to have: 96.3% Sensitivity 99.1% Specificity 97.8% Accuracy Frequently asked questions Who is the rapid test for? Nevertheless, if youre infected and still have a low concentration of the virus in your body (and hence, no symptoms) then the test results might not be completely accurate. Here Are the Symptoms for Delta, Omicron Variants, the Flu, and Allergies. Estimates of sensitivity varied considerably between studies, with consistently high specificities. 1 Pack COVID-19 HOTGEN Antigen Rapid Test. We use cookies to improve your experience on our site. This reduces the number of tests that need to be run. Mike DeWine was due to meet President Donald Trump at a Cleveland airport, the governor tested positive on a rapid antigen test for the new coronavirus, SARS-CoV-2, that causes the disease COVID-19. ** Swabs for real-time RT-PCR were stored in viral transport media at 39F (4C) and analyzed within 2472 hours of collection. How Accurate Are Rapid COVID Tests? What Research Shows - Healthline Virus was recovered from 34 (46.6%) of 73 positive specimens, including 32 (82.1%) of 39 specimens with concordant positive results and two (11.1%) of 18 with false-negative antigen results; no virus was recovered from 16 specimens with false-positive antigen test results. At university A, real-time RT-PCR was performed using the CDC 2019-nCoV real-time RT-PCR diagnostic panel for detection of SARS-CoV-2. No potential conflicts of interest were disclosed. A positive test result indicates that the samples contained novel coronavirus antigen. 7 tips to get an accurate result. They come in disposable plastic cassettes, similar to over-the-counter pregnancy tests. https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/prevention.html. The two specimens with false-negative antigen results that were culture-positive were from two symptomatic participants who had specimens collected at day 2 and day 4 after symptom onset.***. Table 1 - Eurosurveillance Sect. : CD013705. Rapid antigen tests are less good at ruling out infection in symptomatic people - individuals who receive a negative rapid antigen test result may still be infected. Alternatively, where RT-PCR is available, rapid antigen tests could be used to select which people with symptoms require further testing with RT-PCR, thereby reducing the burden on laboratory services. endstream If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Using summary results for symptomatic people tested during the first week after symptoms began, if 1000 people with symptoms had the antigen test, and 50 (5%) of them really had COVID-19: 45 people would test positive for COVID-19. When tests were used according to manufacturer instructions, average sensitivities by brand ranged from 34.3% to 91.3% in symptomatic participants (20 assays with eligible data) and from 28.6% to 77.8% for asymptomatic participants (12 assays). (English language not guaranteed) This . Measles Outbreak in American Samoa Sickens 49, What are the Signs? Heres how they all stack up, in order of most to least sensitive. Results from different test brands varied, and relatively few studies directly compared one test brand with another. The CDC has issued a warning for travelers after two outbreaks of the Marburg virus. Virus culture was attempted on all antigen-positive or real-time RT-PCRpositive specimens. In vitro diagnostics EUAs. Others agree about the need for decentralized testing. 3 0 obj This test can be used on children as young as 2 years old and on individuals with or without symptoms or other epidemiological reasons to suspect COVID-19. 15 0 obj This review updates our previous review and includes evidence published up to 8 March 2021. It works whether you are showing. These tips come from analysing instructions on the TGA website about how to use approved rapid antigen tests. Although antigen tests are faster and the number of tests being run can be easily scaled up, they have a high false-negative rate with as many as half of negative results inaccurate. What are rapid point-of-care antigen tests for COVID-19? As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a single infectious agent worldwide. Gently insert the swab into your nostril until you feel some resistance. Beijing Hotgen Biotech Co.,Ltd Add. Many commercially available rapid antigen tests have not been evaluated in independent validation studies. True positive = antigen-positive and real-time RT-PCRpositive; false negative = antigen-negative and real-time RT-PCRpositive; false positive = antigen-positive and real-time RT-PCRnegative; true negative = antigen-negative and real-time RT-PCRnegative; these definitions do not reflect results from viral culture. Copyright 2022 Hotgen All Rights Reserved. Ultimately though, the Centers for Disease Control and Prevention (CDC) states that, with all at-home tests, success rates depend largely on how well an individual can follow the specific directions. We included 155 study cohorts (described in 166 study reports, with 24 as preprints). This requirement was fullfilled by 96/122 tests, including tests from Teda (Anbio), Hotgen, and Clongene. hb```9lB Of these, 18 people (0.2%) would actually have COVID-19 (false negative result). In an article on STAT News, Drs. The test can detect the presence of the new coronaviruss RNA in a saliva sample in as little as 30 minutes. FlowFlex COVID-19 Antigen Home Test $10 If you want to stock up on at-home tests, FlowFlex is your most affordable option. Antigen tests vary in sensitivity. In people with signs and symptoms of COVID-19, sensitivities are highest in the first week of illness when viral loads are higher. <>stream 45 C.F.R. More direct comparisons of test brands are needed, with testers following manufacturers instructions. 241(d); 5 U.S.C. Non-Hispanic ethnicity represented for all White, Black/African-American, Asian/Pacific Islander, American Indian/Alaska Native, Other/Unknown/Multiple races. Accuracy: 97.31%. Hotgen Corona Quick Test Self-Test Antigen Test for SARS-CoV-2, Pack of 10. Beijing Hotgen Biotech Co.,Ltd Add. The Hotgen COVID self-test is CE-marked and approved for home use by the German Federal Institute for Drugs and Medical Devices (BfArM). E25 has developed a paper test strip that can detect SARS-CoV-2 infection within 15 minutes with a saliva sample. What used to require a trip to the local health care center or testing site now can be done in the comfort of your own home, without long waiting periods to find out your results. <>/MediaBox[0 0 595.29999 841.90002]/Parent 2 0 R/Resources<>/ProcSet[/PDF/Text]>>/Type/Page>> Background Since its establishment in August 2020, the joint UK Health Security Agency ( UKHSA) Porton Down and University of Oxford SARS-CoV-2 lateral flow antigen test validation cell has. Hospitals and other places that need highly accurate results will continue to use this type of test. You dont even have to leave the comfort of your own home. Sensitivity, specificity, PPV, and NPV were calculated for antigen testing compared with real-time RT-PCR results. <>/MediaBox[0 0 595.29999 841.90002]/Parent 2 0 R/Resources<>/ProcSet[/PDF/Text]>>/Type/Page>> With the recently growing market for them, it's hard to tell which ones to invest in keeping around the house. endobj This is likely to be because people have the most virus in their system in the first days after they are infected. endobj Only 23 studies compared two or more brands of test. Rapid antigen tests are less accurate when used in people with no symptoms of COVID-19. <>/MediaBox[0 0 595.29999 841.90002]/Parent 2 0 R/Resources<>/ProcSet[/PDF/Text]>>/Type/Page>> Different from any of the other antigen tests, the Lucira test is a molecular test, which means that, unlike the antigen tests, it detects the virus that causes COVID-19, so it has a much higher degree of accuracy (this particular test has a 98 percent degree of accuracy). endobj Paired nasal swabs were collected from students, faculty, staff members, and other affiliates at two Wisconsin university campuses during university-based testing programs. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. While it has not been fully FDA-approved, it is cleared for Emergency Use Authorization (EUA) and is fairly affordable as well. This test can be used on children as young as 2 years old and on individuals with or without symptoms or other epidemiological reasons to suspect COVID-19. COVID19: HOTGEN-Antigen-Schnelltest richtig anwenden Alfried Krupp Krankenhaus 1.29K subscribers Subscribe 246K views 2 years ago ALFRIED KRUPP KRANKENHAUS IN RTTENSCHEID In unserem. The emergency use of this product is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Federal Food, Drug, and Cosmetic Act, 21 U.S.C. Questions or messages regarding errors in formatting should be addressed to PDF Coronavirus 2019-nCoV Test Gold) Data - plentymarkets Atlanta, GA: US Department of Health and Human Services, CDC; 2020. Evaluation of the specificity and accuracy of SARS-CoV-2 rapid antigen self-tests compared to RT . 12 0 obj This can create confusion, especially when people arent aware of what type of test theyve had done. The main results are based on 152 studies investigating a total of 100,462 nose or throat samples; COVID-19 was confirmed in 16,822 of these samples. 3501 et seq. Compared with real-time reverse transcription-polymerase chain reaction (RT-PCR) testing, the Sofia antigen test had a sensitivity of 80.0% and specificity of 98.9% among symptomatic persons; accuracy was lower (sensitivity 41.2% and specificity 98.4%) when used for screening of asymptomatic persons. endobj Other study characteristics were extracted by one review author and checked by a second. <>/MediaBox[0 0 595.29999 841.90002]/Parent 2 0 R/Resources<>/ProcSet[/PDF/Text]>>/Type/Page>> URL addresses listed in MMWR were current as of Dr. Michael Mina, a professor of epidemiology at Harvard T.H. See additional information. 1CDC COVID-19 Response Team; 2Epidemic Intelligence Service, CDC; 3Wisconsin Department of Health Services; 4School of Medicine and Public Health, University of Wisconsin-Madison; 5Laboratory Leadership Service, CDC; 6Agency for Toxic Substances and Disease Registry, Atlanta, Georgia; 7University of Wisconsin-Oshkosh; 8University Health Services, University of Wisconsin-Madison; 9Wisconsin Veterinary Diagnostic Laboratory, University of Wisconsin-Madison; 10Winnebago County Health Department, Oshkosh, Wisconsin; 11Wisconsin State Laboratory of Hygiene. Test kit name, specifications, batch number Name: Novel Coronavirus 2019-nCoV Antigen Test (Colloidal Gold) Specification: 40 Tests/Kit; For symptomatic participants, summary sensitivities for seven assays were 80% or more (meeting acceptable criteria set by the World Health Organization (WHO)). Although rapid antigen tests are selling out at supermarkets and pharmacies across the east coast, and the best rapid antigen test is the one you can get soonest, theres still an opportunity to shop around when purchasing rapid antigen tests online. Ct values for specimens with false-negative antigen results were significantly higher compared with antigen- and real-time RT-PCR-positive specimens (mean N1 Ct = 32.3 versus 23.7; p<0.01) (Figure). Rapid tests have always worked best when people are showing symptoms and have high viral loads, and so far, real-world data suggests they're holding up well on that front. The WHO acceptable performance criterion of 97% specificity was met by 17 of 20 assays when tests were used according to manufacturer instructions, 12 of which demonstrated specificities above 99%. In people with symptoms, some rapid antigen tests are accurate enough to replace RT-PCR, especially for ruling in the presence of infection. DOI: http://dx.doi.org/10.15585/mmwr.mm695152a3external icon. The 152 studies of single test applications reported 228 evaluations of antigen tests. endobj Fatigue and body aches are symptoms of both the flu and COVID-19, but the flu usually doesnt cause shortness of breath. 7 0 obj We included evaluations of single applications of a test (one test result reported per person) and evaluations of serial testing (repeated antigen testing over time). Lu X, Wang L, Sakthivel SK, et al. At university B, only students who were quarantined during September 28October 6 after exposure to persons with COVID-19 could participate. Unfortunately, there are mixed reviews regarding its accuracy. Possible incorrect test result (see Warnings and Result, What do I have to pay attention to in order to get the most exa, Always follow the instructions for use exactly. Most of these tests are currently intended for professional use only, in labs and medical centers. He's a board editor with the International Journal of Clinical Research, and has published several research papers during his career. a red line appears. All the steps, from sample collection to test interpretation, can be done at home or work. endobj Sensitivity96.30% 99.13% Accuracy: 97.76%. 6 0 obj Rapid antigen testing has become widely popular in recent months, with the surge in cases and variants, and several big-time manufacturers have begun producing them on a larger scale. Ct values represent cycle thresholds for the N1 target probe during SARS-CoV-2 real-time RT-PCR; Ct values are represented on the y-axis in descending order to indicate that lower Ct values represent higher levels of RNA in the specimen. More evidence is needed to understand the accuracy of rapid testing in people without symptoms and the extent to which repeated testing strategies can lead to reduced transmission, either for tests carried out at home or in non-healthcare settings such as schools. At 0.5% prevalence using summary data for asymptomatic people, where testing was widely available and where epidemiological exposure to COVID-19 was suspected, resulting PPVs would be 38% to 52%, meaning that between 2 in 5 and 1 in 2 positive results will be false positives, and between 1 in 2 and 1 in 3 cases will be missed. Dozens of people who took a rapid SARS-CoV-2 test developed by biotech company Quidel at a Manchester, Vermont, clinic in July were told they had the virus. Even though the test isnt perfect, its far better than what were doing now, which is testing hardly anyone without symptoms, they wrote, in part due to concerns about testing accuracy.. 16 0 obj Of these, 30 people (48%) would not have COVID-19 (false positive result). Because no user errors could be identified, the false-positive results were included in analysis. This test would be absolutely suitable for a doctors office, or a hotel before people check in, or the airport before people get on a plane, said Dr. Mark Brunswick, Sorrentos senior vice president of regulatory affairs. Among asymptomatic participants, antigen test sensitivity was 41.2%, specificity was 98.4%, and PPV in this population was 33.3%. Sect. All eight initial paired swabs from these participants were negative on real-time RT-PCR. Cochrane Database of Systematic Reviews 2022, Issue 7. <> For that to happen, the tests need to be simple, cheap, and available everywhere. 1 piece Sampling tube with cap and extraction buffer. part 56; 42 U.S.C. They help us to know which pages are the most and least popular and see how visitors move around the site. Virus was isolated from 34 (46.6%) of 73 antigen-positive or real-time RT-PCRpositive nasal swab specimens, including two of 18 that were antigen-negative and real-time RT-PCRpositive (false-negatives). endobj uuid:dbb16d7a-1dd1-11b2-0a00-5b0000000000 Coronavirus disease 2019 (COVID-19): interim considerations for SARS-CoV-2 testing in correctional and detention facilities. endobj COVID-19 In Vitro Diagnostic Medical Device - detail Dinnes J, Sharma P, Berhane S, van Wyk SS, Nyaaba N, Domen J, Taylor M, Cunningham J, Davenport C, Dittrich S, Emperador D, Hooft L, Leeflang MMG, McInnes MDF, Spijker R, Verbakel JY, Takwoingi Y, Taylor-Phillips S, Van den Bruel A, Deeks JJ. CDC. Hotgen Corona Rapid Test Self-Test, Pack of 5 - Amazon JAMA Netw Open 2020;3:e2016818. This is the second update of this review, which was first published in 2020. (Disease Course 5-7 Days) High AccuracySpecicity and Sensitivity No need instrument, get results in 15 minutes Room temperature storage Sample : Human Anterior Nares Swab Detect the presence of viral proteins Identify acute or early infection Sensitivity96.30% Spe i i ity99.13% Accuracy: 97.76%. This test is also FDA-approved and comes with a promise of providing results with 95 percent accuracy. Here's Why We Can't Rely on Rapid Coronavirus Testing - Healthline Swabs for antigen testing were analyzed according to the manufacturers instructions. It is currently unavailable on Amazon but costs $30 to $70 on average, and results are available in about 15 minutes. At-Home OTC COVID-19 Diagnostic Tests | FDA It is more expensive than some of the others, and results are available in 30 minutes. All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Currently, COVID-19 infection is confirmed by a laboratory test called RT-PCR, which uses specialist equipment and often takes at least 24 hours to produce a result. Greenwich to sue Latham over homophobic tweet, Not going to be 80: Michael J Foxs emotional admission, Watch: Paramedic farewelled, Greenwich legal action, Referee assault, Indigenous Voice is wrong and potentially quite dangerous: Abbott, Man in court for shocking attack on soccer referee, NRL concedes knock-on error on crucial golden point call for Raiders, You think Im old?: President Joe Biden roasts Rupert Murdoch, Home values rise as housing market downturn wanes, Search for missing man continues after body found.

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